Great Plague of London, epidemic of plague that ravaged London, England, from 1665 to 1666. The peak of the epidemic was the week of 19–26 September 1665 when London mortality bills recorded 7,165 deaths from plague.

Death in the form of plague. City records indicate that some 68,596 people died during the epidemic, though the actual number of deaths is suspected to have exceeded 100,000 out of a total population estimated at 460,000. The Great Plague Plague had been around in England for centuries but in 1665 it was Stuart London that suffered. Samuel Pepys, diarist supreme, told the story with emotion and detail, and much of what he saw is very well known. The Great Plague of London was a major moment in English history, but it certainly wasn't a great time for the English people.

Bell also wrote “The Great Fire of London in 1666” the city’s second catastrophe in two years.

Plague had been around in England for centuries but in 1665 the so-called Great Plague hit the country – though it was Stuart London that took the worst of the plague. The plague was only finally brought under control in 1666 when the Great Fire of London burned down the areas most affected by plague – the city slums inhabited by the poor. City records indicate that some 68,596 people died during the epidemic. People called it the Black Death, black for the colour of the tell-tale lumps that foretold its presence in a victim's body, and death for the inevitable result. Plague usually resulted in death, normally within a week of the first symptoms. It crept up upon an unsuspecting urban population in London, and then roared across the country. In The Great Plague, historian A. Lloyd Moote and microbiologist Dorothy C. Moote provide an engrossing and deeply informed account of this cataclysmic plague year. London during the Great Plague. The first few days though were without symptom and someone fleeing the dead could be a good carrier.

Neither was a novelty. The Black Death In the year 1665 death came calling on the city of London. The Great Plague. Bubonic Plague was known as the Black Death and had been known in England for centuries. It was a ghastly disease. When can something be great, but not good? This is the final plague entry, dated April 4, 1667.

Two of the greatest disasters in London’s history both occurred in the 1660s: plague and fire struck the city in successive years.

This tells the famous story of the village of Eyam in Derbyshire that deliberately isolated itself to stop the spread of the disease to nearby villages. We know a surprising amount of the story through two witnesses. If their new host is a person, the disease can spread to humans too. When a rat dies from the plague, its fleas must find a new host to live on. The Great Plague of London—an epidemic of the infectious disease known as the plague—ravaged London, England, from 1665 to 1666. The plague did not only affect London. During the Great Plague of London (1665-1666), the disease called the bubonic plague killed about 100,000 people in London, England. The bubonic plague was endemic – there were outbreaks in 1603 and 1625 that killed tens of thousands – but neither was as bad as the Great Plague … Bubonic plague is a disease of rodents, especially black rats.

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